nausea; appetite absent/loss of appetite; tight chest/sore tight chest; black diarrhea; feeling sick/feeling sick at the thought of food; chest pain/sore tight chest; fatigue/unusual tiredness; fever; heart palpitations; racing heart (tachycardia); sore when breathing; this is a spontaneous report received from a contactable reporter(s) (consumer or other non hcp) from the regulatory authority. regulatory number: gb-mhra-webcovid-202202162216032410-exz7h. other case identifier(s): gb-mhra-adr 26611749. a 24 year-old female patient (not pregnant) received bnt162b2 (comirnaty), administration date 04feb2022 (batch/lot number: unknown) as dose 3 (booster), single for covid-19 immunisation. the patient's relevant medical history and concomitant medications were not reported. vaccination history included: bnt162b2 (dose 1, single;), for covid-19 immunisation; bnt162b2 (dose 2, single;), for covid-19 immunisation. the following information was reported: diarrhoea (medically significant) with onset feb2022, outcome "not recovered", described as "black diarrhea"; malaise (medically significant) with onset feb2022, outcome "not recovered", described as "feeling sick/feeling sick at the thought of food"; chest pain (medically significant) with onset feb2022, outcome "unknown", described as "chest pain/sore tight chest"; chest discomfort (medically significant) with onset 13feb2022, outcome "not recovered", described as "tight chest/sore tight chest"; nausea (medically significant) with onset 14feb2022, outcome "not recovered", described as "nausea"; decreased appetite (medically significant) with onset 14feb2022, outcome "not recovered", described as "appetite absent/loss of appetite"; fatigue (medically significant) with onset feb2022, outcome "unknown", described as "fatigue/unusual tiredness"; pyrexia (medically significant) with onset feb2022, outcome "unknown", described as "fever"; palpitations (medically significant) with onset feb2022, outcome "unknown", described as "heart palpitations"; tachycardia (medically significant) with onset feb2022, outcome "unknown", described as "racing heart (tachycardia)"; painful respiration (non-serious) with onset feb2022, outcome "unknown", described as "sore when breathing". the patient underwent the following laboratory tests and procedures: sars-cov-2 test: (14feb2022) no - negative covid-19 test. patient has not had symptoms associated with covid-19 patient is not pregnant. patient is not currently breastfeeding. patient has not tested positive for covid-19 since having the vaccine. patient is not enrolled in clinical trial. sore tight chest, sore when breathing. loss of appetite feeling sick at the thought of food. black diarrhea. does your report relate to possible inflammation of the heart (myocarditis or pericarditis) was "yes". no follow-up attempts are possible; information about lot/batch number cannot be obtained. no further information is expected