depression; nosebleed; this is a spontaneous report received from a contactable reporter (other hcp) from the ra. regulatory number: gb-mhra-webcovid-202202171223327480-5dgs3. other case identifier: gb-mhra-adr 26612779. a female patient received bnt162b2 (comirnaty), administration date 01sep2021 (batch/lot number: unknown) as dose 1, single for covid-19 immunisation. the patient's relevant medical history and concomitant medications were not reported. the following information was reported: epistaxis (disability) with onset 16sep2021, outcome "recovered with sequelae", described as "nosebleed"; depression (disability) with onset 01oct2021, outcome "not recovered", described as "depression". clinical course: patient has not had symptoms associated with covid-19. patient was not enrolled in clinical trial. patient has not had symptoms associated with covid-19. no follow-up attempts are possible; information about lot/batch number cannot be obtained. no further information is expected.; sender's comments: linked report(s) : gb-pfizer inc-202200311535 same patient, different events/doses;gb-pfizer inc-202200311534 same patient, different events/doses