pain; joint pain/acute pain in right hip and knee; delayed period; primary immunisation: non-pfizer vaccine; booster: comirnaty; primary immunisation: non-pfizer vaccine; booster: comirnaty; this is a spontaneous report received from a contactable reporter(s) (consumer or other non hcp) from the regulatory authority . the reporter is the patient. regulatory number: gb-mhra-webcovid-202202181246473930-xylml. a 47 year-old female patient (not pregnant) received bnt162b2 (comirnaty), administration date 19dec2021 (batch/lot number: unknown) as dose 3 (booster), single for covid-19 immunisation. relevant medical history included: "depressed mood" (unspecified if ongoing). concomitant medication(s) included: fluoxetine taken for depressed mood. vaccination history included: covid-19 vaccine (dose 2; manufacturer unknown), for covid-19 immunisation; covid-19 vaccine (dose 1; manufacturer unknown), for covid-19 immunisation. the patient had no symptoms associated with covid-19 and was not enrolled in clinical trial. the patient was not breastfeeding at the time of this report. the last menstrual date of the patient was on 16feb2022. the following information was reported: off label use (disability), interchange of vaccine products (disability) all with onset 19dec2021, outcome "unknown" and all described as "primary immunisation: non-pfizer vaccine; booster: comirnaty"; pain (disability), outcome "not recovered", described as "pain"; menstruation delayed (disability) with onset 25dec2021, outcome "recovered" (16feb2022), described as "delayed period"; arthralgia (disability) with onset 12feb2022, outcome "recovered" (16feb2022), described as "joint pain/acute pain in right hip and knee". the patient underwent the following laboratory tests and procedures: sars-cov-2 test: no - negative covid-19 test. the patient experienced acute pain in the right hip and right knee on 15feb2022 which lasted more than 12 hours. the pain disappeared when she got her period.the patient had not been tested positive for covid-19 since having the vaccine. no follow-up attempts are possible; information about lot/batch number cannot be obtained. no further information is expected