similar lump and inflammation present on that right thigh around the injection site; similar lump and inflammation present on that right thigh around the injection site; muscle inflammation; this is a spontaneous report received from a contactable reporter(s) (consumer or other non hcp) from the regulatory agency (ra). regulatory number: gb-mhra-webcovid-202202182020489140-632xc (ra). other case identifier(s): gb-mhra-adr 26622922 (ra). a 35 year-old female patient (not pregnant) received bnt162b2 (comirnaty), administered in thigh right, administration date 13oct2021 (batch/lot number: unknown) as dose 3 (booster), single for covid-19 immunisation. the patient's relevant medical history and concomitant medications were not reported. patient has not had symptoms associated with covid-19. patient is not currently breastfeeding. patient is not enrolled in clinical trial. vaccination history included: bnt162b2 (dose 1), for covid-19 immunisation; bnt162b2 (dose 2), for covid-19 immunisation, reaction(s): "inflammation", "big lump of the left arm (where i had an covid vaccine)". the following information was reported: vaccination site inflammation (medically significant), outcome "recovered", vaccination site mass (medically significant), outcome "unknown" and all described as "similar lump and inflammation present on that right thigh around the injection site"; myositis (medically significant) with onset 05feb2022, outcome "not recovered", described as "muscle inflammation". the patient had the inflammation and big lump of the left arm (where she had an covid vaccine) 2 months after the 2nd dose of vaccine. the inflammation lasted for 3-4 days and recurred every month. she had blood tests and scan, apart from esr of 20, no abnormality was detected. and then she had third dose of covid vaccine on the thigh to avoid the reaction on the arm. 3 months later the similar lump and inflammation present on that right thigh around the injection site. all her covid vaccine are pfizer vaccines. no follow-up attempts are possible; information about lot/batch number cannot be obtained. no further information is expected. ; sender's comments: linked report(s) : gb-pfizer inc-202200319688 same patient/ product, different dose and similar event