chest pain; fatigue/unusual tiredness; shortness of breath; next day red patch had spread; has a red welt on it; allergy; 3 hours after getting booster the arm has swelled up; this is a spontaneous report received from a contactable reporter(s) (consumer or other non hcp) from the regulatory agency (ra). regulatory number: gb-mhra-webcovid-202202202153027020-ayh77 (ra). other case identifier(s): gb-mhra-adr 26626440 (ra). a 24 year-old female patient received bnt162b2 (comirnaty), administration date 18feb2022 (batch/lot number: unknown) at the age of 24 years as dose 3 (booster), single for covid-19 immunisation. the patient's relevant medical history and concomitant medications were not reported. patient had not had symptoms associated with covid-19. patient was not currently breastfeeding. vaccination history included: bnt162b2 (dose 1), for covid-19 immunisation, reaction(s): "chest pain", "illness"; bnt162b2 (dose 2), for covid-19 immunisation, reaction(s): "chest pain", "illness". the following information was reported: hypersensitivity (medically significant) with onset 18feb2022, outcome "not recovered", described as "allergy"; chest pain (medically significant), outcome "recovered with sequelae", described as "chest pain"; fatigue (medically significant), outcome "unknown", described as "fatigue/unusual tiredness"; dyspnoea (medically significant), outcome "unknown", described as "shortness of breath"; peripheral swelling (medically significant) with onset 18feb2022, outcome "unknown", described as "3 hours after getting booster the arm has swelled up"; rash (medically significant) with onset 19feb2022, outcome "unknown", described as "next day red patch had spread"; urticaria (medically significant) with onset 18feb2022, outcome "unknown", described as "has a red welt on it". the patient underwent the following laboratory tests and procedures: sars-cov-2 test: (19feb2022) negative. clinical course: the patient had chest pains and illness with first 2 doses. she received booster and had no illness. however, around 3 hours after getting booster the arm had swelled up and had a red welt on it. next day red patch had spread and more of arm was swollen. no follow-up attempts are possible; information about lot/batch number cannot be obtained. no further information is expected.; sender's comments: linked report(s) : gb-pfizer inc-202200326096 same patient, different dose, different events;gb-pfizer inc-202200326100 same patient, different dose, different events