chest pain; with immediate swelling of the tongue; immediate allergic reaction; this is a spontaneous report received from a contactable reporter(s) (consumer or other non hcp) from the regulatory authority-web. the reporter is the patient. a 40 year-old female patient (unknown if pregnant) received bnt162b2 (comirnaty) (batch/lot number: unknown) as dose 2, single for covid-19 immunisation. relevant medical history included: "congenital cataract" (unspecified if ongoing), notes: in the right eye; "operated" (unspecified if ongoing), notes: i was 18 years old, which does not allow me to take hormones because of facial paralysis; "facial paralysis" (unspecified if ongoing); "headaches on the right side" (unspecified if ongoing), notes: on the right side; "hypotension" (unspecified if ongoing); "herpes" (unspecified if ongoing). the patient's concomitant medications were not reported. vaccination history included: covid-19 vaccine (dose 1, single, manufacturer unknown), for covid-19 immunization, reaction(s): "allergic reaction", "swelling of the hand, arm, neck"; covid-19 vaccine (dose 1, single, manufacturer unknown), for covid-19 immunization, reaction(s): "swelling of the hand, arm, neck". the following information was reported: chest pain (medically significant), outcome "unknown", described as "chest pain"; swollen tongue (medically significant), outcome "recovered", described as "with immediate swelling of the tongue"; hypersensitivity (medically significant), outcome "unknown", described as "immediate allergic reaction". the clinical course of events was as follows: in all 3 vaccinations patient had immediate allergic reaction with swelling of the hand, arm, neck in 1, chest pain with immediate swelling of the tongue 2.3 and facial paraesthesia on the left. description: edema, facial paresthesia, chest pain, swelling of tongue - actions taken (intramuscular cortisone, in the vein and orally with tablets.) - impact on quality of life (10/10) - covid 19 comirnaty vaccine (pfizer): injection site (left shoulder) booster dose number (3). sender comment: on 16feb2022 received update - referred to by the reporter: patient was currently undergoing cortisone treatment at home. the swelling of her tongue has subsided but the tingling sensation on the left side of her face persists. reporter comment: congenital cataract in the right eye, operated when i was 18 years old, which does not allow me to take hormones because of facial paralysis, headaches on the right side, hypotension, herpes. no other allergies evident. no follow-up attempts are possible; information about lot/batch number cannot be obtained. no further information is expected.; reporter's comments: congenital cataract in the right eye, operated when i was 18 years old, which does not allow me to take hormones because of facial paralysis, headaches on the right side, hypotension, herpes. no other allergies evident.; sender's comments: linked report(s) : it-pfizer inc-202200307378 same patient/product; different dose and ae.;it-pfizer inc-202200333889 same patient/product; different dose/ae